

“They’re a very, very invisible population,” said Alexis Handal, a University of Michigan professor who co-leads the Michigan Farmworker Project alongside researcher Lisbeth Iglesias-Ríos.
The SWAN Multi-Pollutant Study (MPS) was initiated in 2016 to examine health effects of multiple environmental chemical exposures, including perfluoroalkyl and polyfluoroalkyl substances (PFAS), polychlorinated biphenyls (PCBs), organochlorine pesticides, polybrominated diphenyl ethers (PBDEs), metals, phenols, phthalates, and organophosphate pesticide among midlife women. Funded through two R01 grants by the National Institute of Environmental Health and Sciences (NIEHS), the SWAN MPS specifically investigates 1) obesity, type-2 diabetes and related metabolic endpoints; and 2) reproductive health including sex steroid hormones, age at menopause and ovarian aging).
The 36-year MBHMS follows the daughters of participants in the historic Tecumseh Community Health Study to evaluate the impact of aging-related processes including menopause and the secular increase in obesity on the development and progression of musculoskeletal disease and declines in physical functioning. This study addresses a significant gap in scientific knowledge that impedes our ability to optimize fracture prevention strategies. If our hypotheses prove correct, baseline external bone size may be used as an additional parameter to identify women most likely to lose bone strength rapidly during the MT and who might benefit from early intervention.
Now in its 31th year, the Study of Women’s Health Across the Nation is a multi-site, multi-ethnic longitudinal, study designed to examine the health — physical, biological, psychological and social changes — of women during the midlife and as they age. The resulting research helps scientists, health care providers and women learn how mid-life experiences affect health and quality of life during the midlife and as they age.