Center for Lifecourse Epidemiology and Aging Research (CLEAR): Improving Health, Enhancing Function

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2025

Insomnia Symptoms, Sleep Duration and Risk of Falls in Older Adult Women: Findings from the Study of Women's Health Across the Nation
Authors: Jillian S Baker, Michelle M Hood, Leslie M Swanson, Christopher E Kline, Kelly R Ylitalo, Jane A Cauley, Robin R Green, Carrie A Karvonen-Gutierrez   Journal: The journals of gerontology. Series A, Biological sciences and medical sciences (Dec 13 2025)   PMID: 41389332
Hepatic steatosis in postmenopausal women is characterized by distinct serum extracellular vesicle proteomic signatures
Authors: Patrick Pirrotte, Brooke Lovell, Siobán D Harlow, Carrie A Karvonen-Gutierrez, Michelle M Hood, Ignazio S Piras, Xiumei Wu, Melissa N Martinez, Ritin Sharma, Krystine Garcia-Mansfield, Maya Willey, Johanna K DiStefano   Journal: BMC medicine (Dec 07 2025)   PMID: 41354933
Work as a Predictor of Ethylenethiourea (ETU) Exposure During Pregnancy Among Participants Enrolled in the SEMILLA Birth Cohort Study
Authors: Alexis J Handal, Fadya Orozco, Stephanie Montenegro, Nataly Cadena, Fabián Muñoz, Eileen Ramírez Del Rio, Niko Kaciroti   Journal: Toxics (Nov 27 2025)   PMID: 41304540
Trajectories of Areal Bone Mineral Density Significantly Differ by Patterning of Femoral Neck Area and Bone Mineral Content Across the Menopausal Transition
Authors: Aleda M Leis, Karl J Jepsen, Erin Bigelow, Robert W Goulet, Gregory A Clines, Kerry Richards-McCullough, Yoonkyoung Cho, Tom R Richards, Carrie A Karvonen-Gutierrez   Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (Nov 13 2025)   PMID: 41230819
Converging crises and maternal and child health: colonialism, extreme weather, and COVID-19
Authors: Mislael Valentín-Cortés, Marie S O'Neill, Carlos E Rodríguez-Díaz, Michael R Elliott, Paul J Fleming, Alexis J Handal   Journal: Reproductive health (Nov 05 2025)   PMID: 41194154
Precarious work and chronic disease: lessons learned from the US national agricultural worker survey (1999-2020)
Authors: Lisbeth Iglesias-Rios, Kexin Li, Alexis J Handal, Lu Wang   Journal: Frontiers in public health (Oct 03 2025)   PMID: 41041363
Development and Validation of the Mobility in Middle-Age Questionnaire (MMQ)
Authors: Roee Hayek, Carrie A Karvonen-Gutierrez, Jonathan F Bean, Jack M Guralnik, Kenneth Covinsky, Jay R Hoffman, Michal Azmon, Galit Yogev-Seligmann, Gregory Krautner, Odelyah Saad, Yaniv Nudelman, Rebecca T Brown, 1 more   Journal: The journals of gerontology. Series A, Biological sciences and medical sciences (Sep 29 2025)   PMID: 41017642
An Exposome-Wide Interaction Study to Identify Hidden Environmental Factors Affecting Susceptible Populations: Application to Chemical-Social Vulnerability Interactions on Cognitive Function
Authors: Sung Kyun Park, Erika Walker, Laura Arboleda-Merino, Samuel Fansler, Lauren Y M Middleton, Xin Wang, Bhramar Mukherjee, Belinda L Needham, Kelly M Bakulski   Journal: medRxiv : the preprint server for health sciences (Sep 26 2025)   PMID: 41001512
Contrast Sensitivity Impairment Is Associated With Limitations of Physical Functioning and Activities of Daily Living Among Older Adults
Authors: Navasuja Kumar, Mohammed Kabeto, Andrzej T Galecki, Carrie A Karvonen-Gutierrez, Joshua R Ehrlich   Journal: Journal of aging and health (Sep 02 2025)   PMID: 40891983
The Michigan Farmworker Project: Development and Implementation of a Collaborative Community-Based Research Project Assessing Precarious Employment and Labor Exploitation
Authors: Lisbeth Iglesias-Ríos, Diana E Marin, Kara Moberg, Alexis J Handal   Journal: Journal of community engagement and scholarship (Aug 18 2025)   PMID: 40821696
The association of infertility, miscarriage, stillbirth, and parity with osteoporosis: a pooled analysis of five cohort studies
Authors: Chen Liang, Hsin-Fang Chung, Debra J Anderson, Yvonne T van der Schouw, Nancy E Avis, Carrie A Karvonen-Gutierrez, Annette J Dobson, Gita D Mishra   Journal: Fertility and sterility (Aug 01 2025)   PMID: 40749780
VARIANCE AS A PREDICTOR OF HEALTH OUTCOMES: SUBJECT-LEVEL TRAJECTORIES AND VARIABILITY OF SEX HORMONES TO PREDICT BODY FAT CHANGES IN PERI- AND POSTMENOPAUSAL WOMEN
Authors: Irena Chen, Zhenke Wu, Siobán D Harlow, Carrie A Karvonen-Gutierrez, Michelle M Hood, Michael R Elliott   Journal: The annals of applied statistics (Jul 31 2025)   PMID: 40740693
The relation of heavy or prolonged bleeding during the menopause transition to risk of hysterectomy
Authors: Siobán D Harlow, Michelle M Hood, Alain Mukwege, John F Randolph, Ellen B Gold, Michael R Elliott, Alaina C White, Gail A Greendale   Journal: Women's health (London, England) (Jul 10 2025)   PMID: 40637738
Everybody wants to make money from them: a qualitative study on labor exploitation and labor trafficking of farmworkers in Michigan
Authors: Lisbeth Iglesias-Rios, Alexis J Handal   Journal: Discover social science and health (Jul 07 2025)   PMID: 40620704
Femoral neck width is associated with unique trajectories of age-related hip structural changes and fracture risk within populations of adult women and men
Authors: Karl J Jepsen, Todd L Bredbenner, Carrie A Karvonen-Gutierrez, Aleda M Leis, Michelle M Hood, Sioban D Harlow, John Randolph, Gregory A Clines, Steffenie Merillat, Michael R Elliott, Jane A Cauley, Gail A Greendale, 6 more   Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (Jun 28 2025)   PMID: 40580057
Blood essential trace elements and Alzheimer's disease biomarkers in midlife
Authors: Xin Wang, Kelly M Bakulski, Carrie A Karvonen-Gutierrez, Sung Kyun Park, David Morgan, Brian P Jackson, Roger L Albin, Henry L Paulson   Journal: Frontiers in aging neuroscience (Jun 16 2025)   PMID: 40520530
Dietary Intake Is Associated with Biomarkers of Lead, Arsenic, and Cadmium in a Cohort of Mexican Adolescents
Authors: Yanelli Rodríguez-Carmona, Ana Baylin, Peter Xk Song, Edward Ruiz-Narvaez, Cindy Leung, Alejandra Cantoral, John D Meeker, Niladri Basu, Martha María Tellez-Rojo, Karen E Peterson, Sung Kyun Park   Journal: The Journal of nutrition (Jun 06 2025)   PMID: 40480419
The Relation between Systemic Inflammation and the Menopause Transition: The Study of Women's Health Across the Nation
Authors: Samar R El Khoudary, Xirun Chen, Meiyuzhen Qi, Karen A Matthews, Arun Karlamangla, Ellen B Gold, Sioban D Harlow, Rebecca C Thurston, Hadine Joffe, Jelena Pavlovic, Gail A Greendale   Journal: The Journal of clinical endocrinology and metabolism (Mar 24 2025)   PMID: 40123296
Abnormal uterine bleeding is associated with fatigue during the menopause transition
Authors: Siobán D Harlow, Ellen B Gold, Michelle M Hood, Alain A Mukwege, John F Randolph, Gail A Greendale   Journal: Menopause (New York, N.Y.) (Mar 11 2025)   PMID: 40067756
Sleep Timing, Sleep Timing Regularity, and Cognitive Performance in Women Entering Late Adulthood: The Study of Women's Health Across the Nation (SWAN)
Authors: Leslie M Swanson, Michelle M Hood, Rebecca C Thurston, Meryl A Butters, Christopher E Kline, Howard M Kravitz, Nancy E Avis, Genevieve Neal-Perry, Hadine Joffe, Siobán D Harlow, Carol A Derby   Journal: Sleep (Feb 15 2025)   PMID: 39955263
Experiences of women farmworkers in Michigan: Perspectives from the Michigan Farmworker Project
Authors: Alexis J Handal, Lisbeth Iglesias-Rios, Mislael A Valentín-Cortés, Marie S O'Neill   Journal: American journal of community psychology (Feb 14 2025)   PMID: 39949185
Endocrine-Disrupting Chemicals and Female Reproductive Aging
Authors: Jiaxin Wu, Siobán D Harlow, John F Randolph, Ellen B Gold, Sung Kyun Park   Journal: Seminars in reproductive medicine (Jan 29 2025)   PMID: 39879998

2024

Self-reported history of physical intimate partner violence and longitudinal cognitive performance in midlife women
Authors: Jillian S Baker, Gail A Greendale, Michelle M Hood, Arun S Karlamangla, Siobán D Harlow   Journal: Women's health (London, England) (Dec 21 2024)   PMID: 39707890
Serum fatty acid profiles in systemic lupus erythematosus and patient reported outcomes: The Michigan Lupus Epidemiology & Surveillance (MILES) Program
Authors: Kristen N Gilley, Jenifer I Fenton, Suzanna M Zick, Kexin Li, Lu Wang, Wendy Marder, W Joseph McCune, Raghav Jain, Sidney Herndon-Fenton, Afton L Hassett, Kamil E Barbour, James J Pestka, Emily C Somers   Journal: Frontiers in Immunology, Volume 15 - 2024 (Dec 17 2024)   Link: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1459297/full
Advancing research on greenspace and climate-sensitive adverse birth outcomes for equity and impact
Authors: Nazeeba Siddika, Carina J Gronlund, Alexis J Handal, Marie S O'Neill   Journal: Environmental epidemiology (Philadelphia, Pa.) (Nov 14 2024)   PMID: 39539756
Exposure to air pollution is associated with adipokines in midlife women: The Study of Women's Health Across the Nation
Authors: Xin Wang, Carrie A Karvonen-Gutierrez, Peter Mancuso, Ellen B Gold, Carol A Derby, Howard M Kravitz, Gail Greendale, Xiangmei Wu, Keita Ebisu, Joel Schwartz, Sung Kyun Park   Journal: The Science of the total environment (Nov 02 2024)   PMID: 39488293
Evaluation of test-negative design estimates of influenza vaccine effectiveness in the context of multiple, co-circulating, vaccine preventable respiratory viruses
Authors: Aleda M Leis, Abram Wagner, Brendan Flannery, Jessie R Chung, Arnold S Monto, Emily T Martin   Journal: Vaccine (Oct 30 2024)   PMID: 39476473
The Study of Environmental Exposure of Mothers and Infants Impacted by Large-Scale Agriculture (SEMILLA): Description of the Aims and Methods of a Community-Based Birth Cohort Study
Authors: Alexis J Handal, Fadya Orozco, Stephanie Montenegro, Nataly Cadena, Fabián Muñoz, Eileen Ramírez Del Rio, Niko Kaciroti   Journal: Children (Basel, Switzerland) (Sep 28 2024)   PMID: 39334577
Diabetes and uterine fibroid diagnosis in midlife: Study of Women's Health Across the Nation (SWAN)
Authors: Susanna D Mitro, L Elaine Waetjen, Catherine Lee, Lauren A Wise, Eve Zaritsky, Siobán D Harlow, Samar R El Khoudary, Nanette Santoro, Daniel H Solomon, Rebecca C Thurston, Monique M Hedderson   Journal: The Journal of clinical endocrinology and metabolism (Sep 11 2024)   PMID: 39257183
Associations of serum persistent organic pollutant concentrations with incident diabetes in midlife women: the Study of Women's Health Across the Nation Multi-Pollutant Study
Authors: Amelia Grant-Alfieri, William H Herman, Deborah J Watkins, Stuart Batterman, Carrie Karvonen-Gutierrez, Sung Kyun Park   Journal: Environmental research (Jul 11 2024)   PMID: 38992756
The Michigan Farmworker Project: A Community-Based Participatory Approach to Research on Precarious Employment and Labor Exploitation of Farmworkers
Authors: Lisbeth Iglesias-Rios, Mislael Valentín-Cortés, Paul J Fleming, Marie S O'Neill, Alexis J Handal   Journal: Labor studies journal (Jun 28 2024)   PMID: 38939876
Determinants of urinary dialkyl phosphate metabolites in midlife women: the Study of Women's Health Across the Nation Multi-Pollutant Study (SWAN-MPS)
Authors: Sung-Hee Seo, Stuart Batterman, Carrie A Karvonen-Gutierrez, Sung Kyun Park   Journal: Journal of exposure science & environmental epidemiology (May 08 2024)   PMID: 38719906
Neighborhood physical environments and change in cardiometabolic risk factors over 14 years in the study of Women's health across the nation
Authors: Bradley M Appelhans, Brittney S Lange-Maia, Chen Yeh, Elizabeth A Jackson, Mary D Schiff, Emma Barinas-Mitchell, Carol A Derby, Carrie A Karvonen-Gutierrez, Imke Janssen   Journal: Health & place (May 02 2024)   PMID: 38696876
Changes in Adipose Tissue and Circulating Concentrations of Persistent Organic Pollutants in Midlife Women
Authors: Amelia Grant-Alfieri, Amila Devasurendra, Stuart Batterman, Carrie Karvonen-Gutierrez, Sung Kyun Park   Journal: Environment & health (Washington, D.C.) (Apr 25 2024)   PMID: 38660427
Precarious Work and Housing for Michigan Farmworkers During the COVID-19 Pandemic and Beyond
Authors: Lisbeth Iglesias-Rios, Alexa Kort, Alexis J Handal   Journal: Journal of agromedicine (Apr 23 2024)   PMID: 38651537
Does everyday discrimination account for the increased risk of vasomotor symptoms in Black women?: the Study of Women's Health Across the Nation (SWAN)
Authors: Alexis N Reeves, Tené T Lewis, Michelle M Hood, Rebecca C Thurston, Nancy E Avis, Sherri-Ann M Burnett-Bowie, Yamnia I Cortés, Genevieve Neal-Perry, Siobán D Harlow   Journal: Menopause (New York, N.Y.) (Apr 10 2024)   PMID: 38595299
Race/Ethnicity and Incidence of Pelvic Organ Prolapse in Midlife Women: The Study of Women's Health Across the Nation
Authors: Alain Mukwege, Siobán D Harlow, Michelle M Hood, Barbara D Reed, Sheila A Dugan, Janis M Miller   Journal: Journal of women's health (2002) (Mar 29 2024)   PMID: 38551169
Structural differences contributing to sex-specific associations between FN BMD and whole-bone strength for adult White women and men
Authors: Karl J Jepsen, Erin M R Bigelow, Robert W Goulet, Bonnie T Nolan, Michael A Casden, Kathryn Kennedy, Samantha Hertz, Chandan Kadur, Gregory A Clines, Aleda M Leis, Carrie A Karvonen-Gutierrez, Todd L Bredbenner   Journal: JBMR plus (Mar 25 2024)   PMID: 38523663
The association between incarceration and housing insecurity and advanced immune age during late life
Authors: Lauren MacConnachie, Yuan S Zhang, Mateo Farina, Carmen Gutierrez, Andrew Hoover, Yuelin He, Allison E Aiello, Grace A Noppert   Journal: Social science & medicine (1982) (Mar 10 2024)   PMID: 38461610
Comorbidity clusters among adults with cerebral palsy: A latent class analysis
Authors: Aleda M Leis, Edward A Hurvitz, Daniel G Whitney   Journal: American journal of preventive medicine (Jan 26 2024)   PMID: 38278372
Heavy Metals and Trajectories of Anti-Müllerian Hormone During the Menopausal Transition
Authors: Ning Ding, Xin Wang, Siobán D Harlow, John F Randolph, Ellen B Gold, Sung Kyun Park   Journal: The Journal of clinical endocrinology and metabolism (Jan 25 2024)   PMID: 38271266

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